Medicine E log
Thursday , 2nd July.
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Here we discuss our individual patient's problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs.
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Case Discussion :
A 35 year old male who works as supervisor in thermal plant, regular to work, resident of dhamadacheela Nalgonda came with chief complaints of :
- yellowish discolouration of sclera since 8 days
- Pain in the infrascapular region radiating to chest in the apical region since 3 days
- Normal appetite but not feeling well to take food
HOPI :
Patient was apparently asymptomatic 8 days back, then he developed yellowish discolouration of sclera for which he used herbal medicine for 2 days (2 tablets)
Yellow coloured urine is present, no pale coloured stools, No itching. He went to hospital 5 days back used medication for 3 days and he was found having low Hb and jaundice. He noticed cola coloured stools (1 episode).
Pain in the infrascapular region radiating to chest in the apical region since 3 days which was mild, intermittent, does not increase with hand movements. No H/O SOB, giddiness, syncopal attack.
No H/O nausea, vomitings, loose stools, fever, cough, cold, pain abdomen, burning micturition, bleeding PR, joint pains, headache.
History of past illness :
H/o 15 episodes of loose stools and 2-3 episodes of vomiting for 1 day 15 years back, diagnosed with typhoid. H/o blood transfusion 15 yrs back.
H/o Fever, jaundice diagnosed with malaria admitted for 2 days.
No H/o DM, HTN, Asthma, Epilepsy, CAD.
Drug history :
Not allergic to any known drug.
Personal history :
Diet : mixed
Appetite : Normal
Sleep : adequate
Bowel and Bladder : regular
-chronic alcoholic, 2-3 times/month (270ml)
Family history:
Not significant
General Examination :
Patient is conscious,coherent and cooperative. Moderately nourished and well built.
Temperature : Afebrile
Pulse rate : 88bpm
BP : 120/90 mm hg
RR : 16 cycles per min
SPO2 : 98%
GRBS : 121 mg/dl
Signs of pallor and icterus present.
No signs of cyanosis, clubbing, kilonychia, generalised lymphadenopathy and pedal edema.
Systemic Examination :
Respiratory system :
Normal vesicular breath sounds heard
Bilateral air entry present
Dyspnoea- no
Wheeze- no
Position of trachea- central
Breath sounds- vesicular
No Adventitious sounds heard.
CVS :
Cardiac sounds : S1 S2 heard
No murmurs heard
GI Examination :
Inspection :
Shape - obese
Umbilicus - central
All quadrants moving equal on respiration
3 old burn scars are present
No sinuses, dilated veins.
Palpation :
Soft, no tenderness, no local rise of temperature
Liver - not palpable
Spleen - palpable 7cm below coastal margin, enlargement towards umbilicus.
Percussion :
Liver - dull note, heard at right 5th ICS in mid clavicular line till coastal margin
Spleen - dull note heard at left 7th ICS extending 7cm below coastal margin.
Auscultation :
Bowel sounds are heard
CNS :
Patient is conscious, coherent, cooperative well oriented to time place and person.
Speech - normal
No signs of meningeal irritation
Higher mental functions- normal
cranial nerves- intact
motor system- normal
sensory system - normal
Reflexes :
Right Left
Biceps +2 +2
Triceps +2 +2
Supinator +2 +2
Knee +2 +2
Ankle +2 +2
Plantar Flexor Flexor
Based on the above findings, following investigations were sent :
1.Hemogram
2. Serum iron, ferritin
3. Blood for MP - strip test
4. PT , INR
5. Stool bacterial culture and sensitivity
6. Coombs test
7. HbsAg
8. Anti HCV antibodies
9. HIV
10. ECG
11. USG
12. RFT
13. LFT
14. Serum LDH
15. Reticulocyte count
16. Thyroid profile
17. Vit B12 and folic acid
Diagnosis :
Megaloblastic anemia
Bicytopenia with moderate spleenomegaly
Indirect hyperbilirubinemia
Treatment :
1. Inj vitcofol 1000ug/im/od
2. Tab Bplex forte OD
3. Tab Pan 40mg / od
4. Tab Orofer-xt /Po/od
5. Tab MVT OD
6. Monitor BP, PR, RR
Patient is advised to take Vit B12 in following manner :
July 1st to 7th/2020 : Inj vitcofol 1000ug IM 2cc for 7 days
July 14/ 2020 : Inj vitcofol 1000ug IM 2cc
July 21/2020 : Inj vitcofol 1000ug IM 2cc
July 28/2020 : Inj vitcofol 1000ug IM 2cc
Aug 4th 2020 : Inj vitcofol 1000ug IM 2cc
Sep 4th 2020 : Inj vitcofol 1000ug IM 2cc
Oct 4th 2020 : Inj vitcofol 1000ug IM 2cc
Nov 4th 2020 : Inj vitcofol 1000ug IM 2cc
Dec 4th 2020 : Inj vitcofol 1000ug IM 2cc
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